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‘We need to know’: Covid vaccine trial launched for people with immune disorders


a few quotes:

The goal of the study is to help patients who are immunosuppressed understand their level of protection after vaccination.

“There are some people who cannot get vaccinated for whatever reason, or if they do, they don’t produce a response,” she said. “That’s why it’s really important for everybody else who can get a shot and who should produce a response to get vaccinated.”


CDC says fully vaccinated people can stop wearing masks indoors and outdoors Early data suggests that people who are taking medications that suppress their immune system have a significantly weaker response to the vaccine than healthy people. Data has shown a decreased antibody response to the vaccine in those with blood cancers as well as those on medication for inflammatory disorders.

In the organ transplant study, researchers at Johns Hopkins University found that patients taking a particular class of drugs, called anti-metabolites, were less likely to develop an immune response.

“I am quite disappointed that a significant amount of transplant patients did not get a reasonable response from both doses of the vaccine,” said Dr. Dorry Segev, an author of the the study and associate vice chair for research and professor of surgery at Johns Hopkins University.

Segev’s patients in the study have been frustrated as public health restrictions relax for fully vaccinated patients, while they worry about venturing out.


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